As of 3 August 2016, 68 countries and territories (Fig. 1, Table 1) have reported evidence of mosquito-borne Zika virus transmission since 2007 (65 of these countries and territories have reported evidence of mosquito-borne Zika virus transmission since 2015):
51 countries and territories with a first reported outbreak from 2015 onwards (Table 1).
Four countries are classified as having possible endemic transmission or have reported evidence of local mosquito-borne Zika infections in 2016.
13 countries and territories have reported evidence of local mosquito-borne Zika infections in or before 2015, but without documentation of cases in 2016, or with the outbreak terminated.
The United States of America reported mosquito-borne Zika virus transmission for the first time on 29 July 2016.
Since February 2016, 11 countries have reported evidence of person-to-person transmission of Zika virus, probably via a sexual route (Table 2).
As of 3 August 2016, 14 countries or territories have reported microcephaly and other central nervous system (CNS) malformations potentially associated with Zika virus infection or suggestive of congenital infection. No additional countries or territories have reported microcephaly in the last week. Three of the 14 total countries reported microcephaly cases born from mothers in countries with no endemic Zika virus transmission but who reported recent travel history to Zika-affected countries in the WHO Region of the Americas (Table 3).
As of 3 August 2016, the United States Centers for Disease Control and Prevention (USCDC) reported 13 live-born infants with birth defects and six pregnancy losses with birth defects with laboratory evidence of Zika virus infection.
As of 3 August 2016, 15 countries and territories worldwide have reported an increased incidence of Guillain-Barré syndrome (GBS) and/or laboratory confirmation of a Zika virus infection among GBS cases (Table 4).
In Guinea-Bissau, on 29 June 2016, Institute Pasteur Dakar (IPD) confirmed that three of 12 samples tested positive for Zika by PC-R. All 12 samples tested negative against IgM Zika. One additional sample from a recent case also tested positive for Zika virus infection.
